Collagen is an important natural component of our skin's structure. It is also present in our joints, bones and ligaments. In young skin, collagen is abundant and imparts plumpness to the face and other areas of the body, such as our hands. As we age, the amount and quality of collagen in our body decreases, and as a result, wrinkles and creases begin to appear.

MSM or Methylsulfonylmethane is a naturally-occurring compound found in green plants and animal products. Preliminary research suggests MSM may inhibit degenerative changes in joints, while MSM is typically used as an anti-inflammatory to support joint comfort.  There is some evidence that MSM also supports relief from seasonal allergies, but more research is need on this topic.

In joints, the ground substance is known as synovial fluid. It is the substance that gives connective tissue and joints resilience after compression and also reduces friction between bones, tendon and cartilage. Supplementation with glucosamine and chondroitin have been demonstrated to support maintenance of healthy synovial fluid levels, which support joint comfort directly.